Bupron – Major depressive disorders and seasonal affective disorders

depressMajor depressive disorder(MDD) is a kind of illness that is characterized by extreme low moods that range from two weeks to a period of years. Known as major depression, clinical depression or unipolar depression, the illness is experienced by men and women between ages 25- 44, although it is twice as common in women than in men while it least affects those over age 65. MDD also affects male and female teenagers at the same rate and can be characterized by irritability, changes in body weight, hypersomnia, insomnia, tired behaviours, depressed moods, among others.

Seasonal affective disorder, also known as SAD, is a kind of depression that occurs because of changes in seasons. Commonly referred to as winter’s blues, as it occurs in winter for a large percentage, SAD is characterized by moodiness, reduced energy levels, anxiety, pessimism, suicidal thoughts, feelings of worthlessness or guilt, insomnia, too much sleep, changes in body weight, loss of interest in activities, among others. Doctors believe that it may be caused by a lack of sunlight during winter months, as the symptoms start during the fall and end at the end of winter. While SAD can be well treated with sunlight or light therapy, many patients diagnosed with the illness do not respond well to that. Which is where Bupron comes in and saves the day.bupron-srFirst approved as a medication in 1988 by the United States Government and manufactured by GlaxoSmithKline, Bupron is an antidepressant that helps to relieve the symptoms of major depressive disorders and can improve the moods of patients who suffer from these disorders. It also assists the removal of dependence on nicotine, by targeting neurotransmitters and restoring the brain’s chemical balance. (Medline Plus)

Bupropion is recommended by many doctors, due to its manageable side effects and is a norepinephrine – dopamine reuptake inhibitor (NDRI). It is also used as a supporting medication for SSRIs by doctors for patients who do not respond well or completely to SSRI medications. Although some antidepressants do cause weight gain and other severe symptoms, Bupron does not cause many changes in body weight and body functions.

Uses of bupron

Bupron, as earlier noted, is used to treat symptoms of a seasonal affective disorder, major depressive disorder and nicotine dependence. It improves mood, thereby increasing the energy levels of patients and restores chemical balance in the brain.

Properties of bupron

With the active ingredient Bupropion with a molecular formula C13H19Cl2NO and a molecular weight of 276.201 g per molecule, Bupron is an aminoketone and has a similar structure to that of cathinone and amfepramone which are stimulants. It also has a similar structure to phenethylamines. Depending on the brand name, Bupron comes in colours ranging from white, off-white to a dark blue. This, however, does not change or determine the effectiveness of the drug.

Bupropion pillsDosage

As for most antidepressants, you must not chew, break or crush Bupron or its brand names. Daily dosages will be recommended by your doctor, depending on your medical and health history and reactions to NDRIs and SSRIs in the past. Note that is a slow release drug that must not be taken with alcohol or any nicotine dependent drink.

Side effects

Bupron’s side effects could include dizziness, stomach problems, seizures, nausea, dry mouth, among others. By drinking a lot of water and fluids, exercising, using mouthwash to alleviate dry mouth, these symptoms can be addressed. However, if you experience severe versions of these symptoms or others, it is vital that your doctor is informed.


Doctors warn that people with certain medical conditions, including bipolar disorder, should not use Bupron as it may cause seizures. Zyban and Wellbutrin, which are brand names for Bupron, should not be taken together at the same time. Patients who have recently stopped taking alcohol, have eating disorders and other health issues should notify their doctors before using Bupron. It is vital that your doctor is made aware of any other drugs , especially MAO inhibitors that may have been used within a period of two weeks before Bupron is prescribed. This is to prevent dangerous and life-threatening drug interactions from happening. Women with babies should not breastfeed while on this medication.

It is also necessary that patients using Bupron be monitored by parents, guardians or caregivers and changes, either positive or negative, in mood and behaviour reported to their doctors.

Frequently Asked Questions (FAQ)

Can I skip a dose or take two at once?

No, you should not skip on it unless your doctor tells you to. You should also not take two doses at once; take the missed dose only at the time prescribed.

Where can I purchase the drug?

The drug can only be prescribed by a doctor since it is a slow release medication.

What should I do if I experience bad symptoms?

You should inform your doctor immediately if you feel more severe versions of the side effects listed in this article, or call emergency care.