Micronase® (Glyburide)

What is glyburide?

Glyburide is a specially formulated oral medicine for diabetes that controls blood sugar levels. It is also meant to treat type 2 diabetes. The medicine is not for treating type 1 diabetes.This medication may also be used for other purposes not listed below.

Important information

The use of medicine is not for people who are getting treatment with bosentan (Tracleer),if you suffer from a state of diabetic ketoacidosis, or if you have type 1 diabetes.Before you start taking medicine let your doctor know if you have allergy to sulfa drugs,if you have hemolytic anemia, a nerve disorder, kidney disease, or liver disease, or if you have been using insulin or chlorpropamide (Diabinese).You also need to make sure that your blood sugar levels are in control. Low blood sugar or hypoglycemia is often the result of skipping meals, drinking alcohol, lengthy exercising, or are under stress.The common symptoms of low blood sugar include tremor, sweating, trouble concentrating, headache, weakness, or hunger. To get rid of situation always carry hard candy or glucose tablets, milk and orange juice. However, it is very important for your family to know to how to control the situation in emergency.

Before taking this medicine

Before taking the medicine inform your doctor if you are getting treatment with bosentan (Tracleer), if you suffer from a state of diabetic ketoacidosis, or if you have type 1 diabetes.

To take benefits of glyburideyou must inform your doctor if suffering from any of these diseases:

  • Liver or kidney disease
  • Hemolytic anemia
  • A nerve problem affecting functions of body
  • Hemolytic anemia (a lack of red blood cells)
  • If you have allergy to sulfa drugs
  • An enzyme deficiency called G6PD or glucose-6-phosphate dehydrogenase deficiency
  • If you have been using chlorpropamide (Diabinese) or taking insulin
  • if you have taken chlorpropamide in the past 2 weeks

FDA pregnancy category C

It is still unknown whether glyburide will suit the going-to-be born baby or not. So, if you are pregnant or planning to become one then tell your doctor while using this medicine.It is also not known whether glyburide passes into breast milk or if could create trouble a feeding baby. Therefore it is good not to breastfeed a child while using the medicine.

Glyburide side effects

Even though the intake of Gemfibrozilis tolerable for the patient but there are situations when an emergency medical help may be needed. These include difficulty breathing, swelling on lips, throat, tongue or face.

Call your doctor immediately in case you find following symptoms:

  • Drowsiness
  • Diarrhea
  • Feeling short of breath
  • Nausea
  • Vomiting
  • Severe pain in lower back
  • Rapid weight gain
  • Red or swollen gums
  • Jaundice
  • Dark urine
  • Urinating less than normal
  • Severe pain in upper stomach

Other Side Effects:

  • Mild skin rash
  • Fever
  • Throat
  • Flu symptoms
  • Itching
  • Confusion

The above may not be a complete list of side effects. In case you find some unusual side effects then call your doctor immediately or report about the same to FDA at 1-800-FDA-1088 FREE.

What other drugs will affect glyburide?

There are certain drugs that may interact with glyburide, including over-the-counter medicines, prescription, herbal products, and vitamins. Hence it is important to meet your doctor and inform about the same to avoid the risk of side effects of glyburide on lowering your blood sugar.

What happens if I miss a dose?

In case you miss a dose then take the skipped dose as soon as remembers. But the missed dose should only be taken if the next dose is not scheduled to avoid the side effects of overdose.

What happens if I overdose?

In case you take overdose of glyburide then report about the same at the Poison Help line at 1-800-222-122. Severe signs of hypoglycemia contain weakness, vomiting, rapid breathing, confusion, tremors,fainting, trouble speaking, extreme sweating, nausea, seizure (convulsions), and fast heart rate,

What should I avoid while taking glyburide?

The intake of colesevelam should not be made together with glyburide. The use of colesevelam should only be made after 4 hours you take glyburide. Besides, till the time you are using the medicine make sure no alcohol is consumed, no exposure of sunlight is made, and every time you are outside home a protective clothing and sunscreen (SPF 30 or higher) is used.

How should I take glyburide?

Take glyburide as prescribed by the doctor with first meal of the day. Never take the medicine in smaller or larger amount or for longer than recommended as it may increase the risk of side effects. Besides, your doctor may also ask you for certain medical tests like blood sugar test while using this medicine.The common symptoms of low blood sugar (hypoglycemia) include tremor, sweating, trouble concentrating, headache, weakness, or hunger. To get rid of situation always carry hard candy or glucose tablets, milk and orange juice. However, it is very important for your family to know to how to control the situation in emergency.In case of sever problem of hypoglycemia when you find difficulty eating or drinking then use a glucagon injection. Besides, you should know how to use a glucagon emergency injection kit when needed.In older adults the probability of occurring low blood sugar level is more during the intake of medicine.The symptoms of high blood sugar level (hyperglycemia) are fruity breath odor, drowsiness, dry skin, increased urination, weight loss, dry mouth, hunger, increased thirst, and weight loss.It is essential for you to check your blood sugar levels at the time of stress, surgery or medical emergency, travel, illness, or if you skip meals or drink alcohol. Any change in the medication or dosage plan will be done by your doctor.In case of pregnancy also make sure your blood sugar levels are regularly checked. Any change in the glyburide medication or dosage plan will be done by your doctor.Glyburide should be kept at room temperature away from heat and moisture.

Reviews for Glyburide

User Rating: 8.0

For Diabetes, Type 2: My personal experience says that glyburide about 2.5 mg is really good to keep the blood sugar levels low together with Januvia and metformin.

User Rating: 9.0

For Diabetes, Type 2: I am using this medicine two times a day along with Fortamet. It is really good.

User Rating: 10

For Diabetes, Type 2: It is indeed a very good medication. I use it with Metformin. Together they both keep sugar levels in control. I simple words, the drug is a life saver.