Tadalafil is a medication in the class of phosphodiesterase-5 inhibitors. It’s in the company of Sildenafil and Vardenafil. Its actions are mediated through blood vessel smooth muscle relaxation and increase of blood flow to certain areas in the body.
Tadalafil is available under several brand and generic names for treatment of different ailments. The brand names include Cialis and Adcirca manufactured by Eli Lilly and company. Cialis Tadalafil is approved by the FDA for the treatment of erectile dysfunction-ED and benign prostatic hyperplasia-(BPH) symptoms. Adcirca on the other hand is indicated for treatment pulmonary arterial hypertension.Generic brands include; Tadalis, Apcalis, Apcalis oral jelly, Tadacip/ Cipla tadalafil, Tadora, Erectalis, Filda, Edgon,
Tazzle Megalis, Popup and Forzest. All these are indicated for erectile dysfunction only
In pulmonary arterial hypertension Tadalafil helps relax blood vessels and make possible easy flow of blood in your lungs. This allows proper working of your heart and lungs which raises your capacity to exercise. Similarly in erectile dysfunction Tadalafil works by increasing blood flow to the sexual organ and helps a man maintain erection, of course after sexual stimulation. Tadalafil has revitalised the sex life of millions of men in the world and is one of the most appreciated drugs based on their reviews.
Let’s now dive into a bit of detail about the drug and it’s interactions with our bodies. Tadalafil is insoluble in water and slightly soluble in ethanol. It is important to know that some other medications can cause serious adverse effects when used at same time as Tadalafil. Make sure you inform your health care provider of any other medications you are taking. Using Tadalafil while on nitrates for say chest pains is contraindicated. Nitrates+Tadalafil can cause orthostatic hypotension-decrease in blood pressure to dangerous level. Another point to note is that if by any you get penile priapism-erection of penis for more than 5 hours continuous call your doctor. This can injure your penis. If you have any known allergies you should inform your doctor.
Tadalafil is available in different strength. Tadalafil 2.5mg, Tadalafil 5mg, Tadalafil 10mg and Tadalafil 20mg. Tadalafil is taken in oral form- film coated tablets e.g. Cialis and Adcirca. It is also available in jelly form as in the generic Apcalis oral jelly and recently liquid form (Tadalafil Citrate).Tadalafil is a prescription only medication therefore only a qualified medical can prescribe this medication to you.Tadalafil troches designed to dissolve faster are compounded with 10mg and 20mg strengths.
For erectile dysfunction(Adult)
- 10mgs once a day as initial dose and before sexual activity, maintenance dose will be based on a person’s tolerability and efficacy of the drug.
Daily use for ED and Benign prostatic hyperplasia: 5mg daily oral regular time with no regard to sexual activity time
For pulmonary arterial hypertension(Adult)
- Adcirca 40mg daily
Most common Tadalafil side effects include; headache, indigestion, muscle pains, back pains, nausea, dizziness and flushing. Allergic reactions may occur for those allergic to Tadalafil. If any these adverse effects persist inform your doctor immediately. Priapism can occur that is extended erection. Also inform your doctor if this happens.
Tadalafil drug interactions
Interactions may affect how this drug works. They may increase risk of side effects from tadalafil. You need to tell your doctor of all the medications you are using before he/she prescribes tadalafil to you.
It can interact with nitrates like sodium nitroprusside to cause a dangerous fall in blood pressure due to additive/synergistic vasodilation of the vessels. This can cause dizziness, fainting or in extremely rare cases heart failure. Therefore avoid such drugs indicated for anginas.
Alpha blockers e.g. doxazosin have the same effect of lowering blood pressure seriously low levels and dose modification of either Tadalafil or the Alpha blocker medication is therefore necessary
Some medications increase/decrease elimination of tadalafil from the body. For example azoles like ketoconazole increase drug concentrations in the blood setting you up for side effects. Carbamazepine on the other hand increases drug elimination and can cause reduced tadalafil effect on an individual compromising results.
You should never combine this medication with other medications used for erectile dysfunction like Sildenafil (Viagra) or Vardenafil.
Tadalafil Safety and Storage
Store in a cool and dry place at room temperature, do not freeze
Tadalafil shelf life is generally from 2 years to 3 years after date of manufacture. Dispose off any expired medication as directed by your health care provider.
So maybe you are asking yourself “where can I get access to Tadalafil?” Well there are several platforms that one can get Tadalafil from. First of all before we decide where we are going to get our Tadalafil we have to understand that Tadalafil is a prescription medication thus available only with a doctor’s prescription. Therefore your doctor can prescribe it for you and you can get a few tablets under your insurance. In the U.S Tadalafil is only available in the brand versions Cialis and Adcirca. In other places in the world like India and Canada generic versions are approved and available.
With your prescription you can choose to get tadalafil online or from the nearest reputable pharmacy. Buying online has several advantages including cheaper prices and convenience. Without a prescription you can get tadalafil tablets from online pharmacies that offer to give an assessment by online professional pharmacists and online doctors in order to be able to prescribe. Before buying Tadalafil online make sure you have done your research on the particular online pharmacy you have chosen. Ensure they are accredited and verified. Online pharmacies that do not ask for your Tadalafil prescription or offer to assess you for one are suspicious and you should avoid those. In the UK you can buy Tadalafil online from reputable online pharmacies like euroclinix at good prices. In the U.S there are several including Walgreens, CVS and even Rite-aid.
Generic vs Brand Tadalafil
Take for instance Cialis (brand) and Tadacip (Cipla tadalafil-generic); these two work precisely in the same way and with the same efficacy in treatment of erectile dysfunction. Only generic is not approved in countries like the UK and U.S.Generic tadalafil is available at cheaper prices as compared to brand tadalafil. Cialis for example retails at about $160 for just 4 pills while same four tablets off a generic version say Tadalis retail at just $4. Here is a graph showing the disparities in their prices.
Most of generic Tadalafil is available in India and Canada. In fact most are manufactured in India.
To see the best tadalafil prices available for Cialis we’ll compare its price in different reputable pharmacies. It averagely costs about $40 per 10/20mg tablet in the US. From online pharmacies like say Euroclinix it is about $20 per 10/20mg tablet.Below is a graphical representation.
There are coupons and discount cards available for tadalafil both generic and brand versions. Tadalafil manufacturer coupons and discount cards from some online websites and pharmacies to enable cheaper access to Tadalafil. Tadalafil manufacturer coupons, trial offers and savings offers are only available in a few selected pharmacies.
Sildenafil (Viagra) Vs Tadalafil (Cialis)
Let’s first compare their prices;
Tadalafil is slightly more expensive than Sildenafil when it comes to the brand version but have fairly the same price in terms of their generic versions. In the efficacy front Tadalafil is also more efficacious than Sildenafil. It acts faster and lasts for more than 30 hours, sildenafil lasts for about 6 hours. They are both associated with backaches, dizziness and some headache.
Let’s finally take a look at some tadalafil reviews by users of the medication;
- “Tadalis from India has been my choice for a while now after I stopped using brand Cialis due to its price and I want to let you know that they work just the same. Spend less by ordering from India”
- “Since I started using Tadalafil my sex life has been alive and intense. I thank the With a prescription developers of this drug.”
- “I’ve had pulmonary arterial hypertension for a while and this drug Adcirca has really helped in managing my situation. Now my blood pressure is within normal ranges.”
In summary Tadalafil is a medication used for ED,PAH and BPH. It’s available in different generic and brand names. Tadalafil is a prescription only drug. you can get Tadalafil online from online pharmacies or from your nearest pharmacy. You can get coupons, free trials and savings offers from different platforms. Do not get this medication without a prescription.